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1987•Chemistry LettersRequires access

One Evidence Supporting that Thymidylate Synthetase and Thymidine Kinase Are the Rate-determining Enzymes of DNA Synthesis in Regenerating Rat Liver

Ikuyo Tsukamoto, Shosuke Kojo

Open publisher page 16 citations

Abstract

Abstract The integration of the activities of thymidylate synthetase and thymidine kinase is shown to correlate closely with the amount of DNA synthesis. Based on the result, these enzymes are suggested to be the rate-determining enzymes of DNA synthesis in regenerating rat liver.

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What this paper is about

Abstract The integration of the activities of thymidylate synthetase and thymidine kinase is shown to correlate closely with the amount of DNA synthesis. Based on the result, these enzymes are suggested to be the rate-determining enzymes of DNA synthesis in regenerating rat liver.

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OpenAlex reports 16 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Abstract The integration of the activities of thymidylate synthetase and thymidine kinase is shown to correlate closely with the amount of DNA synthesis. Based on the result, these enzymes are suggested to be the rate-determining enzymes of DNA synthesis in regenerating rat liver.

Key concepts: Chemistry, Thymidylate synthase, Thymidine, Thymidine kinase, Enzyme, DNA, DNA synthesis, Biochemistry

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One Evidence Supporting that Thymidylate Synthetase and Thymidine Kinase Are the Rate-determining Enzymes of DNA Synthesis in Regenerating Rat Liver — Research Paper | ScholarLens