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2000•NeurologyOpen access

Effect of subthalamic nucleus stimulation on levodopa-induced dyskinesia in Parkinson’s disease

Valérie Fraix, Pierre Pollak, N. Van Blercom, Junxia Xie, Paul Krack, Adnan Koudsié, Alim Louis Benabid

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Abstract

Article abstract-The authors studied the effect of bilateral subthalamic nucleus stimulation on levodopa-induced dyskinesias in 24 consecutive parkinsonian patients with disabling dyskinesias. The improvement in the three subtypes of levodopa-induced dyskinesias was significant from the third postoperative month and was mainly due to the decrease in the daily dose of levodopa allowed by the stimulation-induced improvement in the motor score.

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What this paper is about

Article abstract-The authors studied the effect of bilateral subthalamic nucleus stimulation on levodopa-induced dyskinesias in 24 consecutive parkinsonian patients with disabling dyskinesias. The improvement in the three subtypes of levodopa-induced dyskinesias was significant from the third postoperative month and was mainly due to the decrease in the daily dose of levodopa allowed by the stimulation-induced improvement in the motor score.

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Available abstract

Article abstract-The authors studied the effect of bilateral subthalamic nucleus stimulation on levodopa-induced dyskinesias in 24 consecutive parkinsonian patients with disabling dyskinesias. The improvement in the three subtypes of levodopa-induced dyskinesias was significant from the third postoperative month and was mainly due to the decrease in the daily dose of levodopa allowed by the stimulation-induced improvement in the motor score.

Key concepts: Levodopa, Subthalamic nucleus, Dyskinesia, Stimulation, Parkinson's disease, Deep brain stimulation, Medicine, Anesthesia

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Effect of subthalamic nucleus stimulation on levodopa-induced dyskinesia in Parkinson’s disease — Research Paper | ScholarLens