1991•Biochemical Systematics and EcologyOpen access

Dinoflagellates cyclize squalene oxide to lanosterol

José‐Luis Giner, Laurent Wünsche, Robert A. Andersen, Carl Djerassi

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Abstract

Direct enzymatic cyclization of squalene oxide to cycloartenol has now been demonstrated in eight algal phyla, whereas five species of dinoflagellates produced lanosterol. This discovery of a lanosterol pathway in dinoflagellates is of clear taxonomic significance. In addition, these findings represent evidence against an assumed biochemical linkage between photosynthesis and cycloartenol production from squalene oxide.

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What this paper is about

Direct enzymatic cyclization of squalene oxide to cycloartenol has now been demonstrated in eight algal phyla, whereas five species of dinoflagellates produced lanosterol. This discovery of a lanosterol pathway in dinoflagellates is of clear taxonomic significance. In addition, these findings represent evidence against an assumed biochemical linkage between photosynthesis and cycloartenol production from squalene oxide.

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Available abstract

Direct enzymatic cyclization of squalene oxide to cycloartenol has now been demonstrated in eight algal phyla, whereas five species of dinoflagellates produced lanosterol. This discovery of a lanosterol pathway in dinoflagellates is of clear taxonomic significance. In addition, these findings represent evidence against an assumed biochemical linkage between photosynthesis and cycloartenol production from squalene oxide.

Key concepts: Cycloartenol, Lanosterol, Squalene, Biology, Sterol, Phylum, Botany, Biochemistry

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