Dinoflagellates cyclize squalene oxide to lanosterol
José‐Luis Giner, Laurent Wünsche, Robert A. Andersen, Carl Djerassi
Abstract
José‐Luis Giner, Laurent Wünsche, Robert A. Andersen, Carl Djerassi
Abstract
Direct enzymatic cyclization of squalene oxide to cycloartenol has now been demonstrated in eight algal phyla, whereas five species of dinoflagellates produced lanosterol. This discovery of a lanosterol pathway in dinoflagellates is of clear taxonomic significance. In addition, these findings represent evidence against an assumed biochemical linkage between photosynthesis and cycloartenol production from squalene oxide.
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Direct enzymatic cyclization of squalene oxide to cycloartenol has now been demonstrated in eight algal phyla, whereas five species of dinoflagellates produced lanosterol. This discovery of a lanosterol pathway in dinoflagellates is of clear taxonomic significance. In addition, these findings represent evidence against an assumed biochemical linkage between photosynthesis and cycloartenol production from squalene oxide.
Key concepts: Cycloartenol, Lanosterol, Squalene, Biology, Sterol, Phylum, Botany, Biochemistry