2005•New England Journal of MedicineRequires access

Genomic Cartography — Presenting the HapMap

Elizabeth G. Phimister

Open publisher page 10 citations

Abstract

Many studies are based on the premise that a sample is representative of the larger body from which it was drawn. An article being published in Nature today1 provides a guide for sampling the human genome in a way that will facilitate the quest for genes that influence susceptibility to disease.The article describes a map of haplotypes, colloquially called the HapMap. (A haplotype is a set of closely linked markers on a single chromosome that tend to be inherited as a group.) It is a logical follow-on from the human genome project and fulfills the need for a new . . .

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What this paper is about

Many studies are based on the premise that a sample is representative of the larger body from which it was drawn. An article being published in Nature today1 provides a guide for sampling the human genome in a way that will facilitate the quest for genes that influence susceptibility to disease.The article describes a map of haplotypes, colloquially called the HapMap. (A haplotype is a set of closely linked markers on a single chromosome that tend to be inherited as a group.) It is a logical follow-on from the human genome project and fulfills the need for a new . . .

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Available abstract

Many studies are based on the premise that a sample is representative of the larger body from which it was drawn. An article being published in Nature today1 provides a guide for sampling the human genome in a way that will facilitate the quest for genes that influence susceptibility to disease.The article describes a map of haplotypes, colloquially called the HapMap. (A haplotype is a set of closely linked markers on a single chromosome that tend to be inherited as a group.) It is a logical follow-on from the human genome project and fulfills the need for a new . . .

Key concepts: International HapMap Project, Human genome, Haplotype, Premise, Genome, Genetics, Computational biology, Genomics

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