1982International Journal of AndrologyOpen access

Lactate dehydrogenase‐X: an isozyme particularly sensitive to gossypol inhibition

Wung‐Wai Tso, Chi‐Sing Lee

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Abstract

The activities of lactate dehydrogenase (all isozymes and isozyme‐X alone) in the presence of a wide range of gossypol were examined in ejaculated mature boar spermatozoa. It was found that LDH‐X, a characteristic isozyme located mainly in primary spermatocytes, is more sensitive than the other isozymes to gossypol inhibition. Its possible role in the male antifertility effect of gossypol is discussed.

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The activities of lactate dehydrogenase (all isozymes and isozyme‐X alone) in the presence of a wide range of gossypol were examined in ejaculated mature boar spermatozoa. It was found that LDH‐X, a characteristic isozyme located mainly in primary spermatocytes, is more sensitive than the other isozymes to gossypol inhibition. Its possible role in the male antifertility effect of gossypol is discussed.

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Available abstract

The activities of lactate dehydrogenase (all isozymes and isozyme‐X alone) in the presence of a wide range of gossypol were examined in ejaculated mature boar spermatozoa. It was found that LDH‐X, a characteristic isozyme located mainly in primary spermatocytes, is more sensitive than the other isozymes to gossypol inhibition. Its possible role in the male antifertility effect of gossypol is discussed.

Key concepts: Gossypol, Isozyme, Lactate dehydrogenase, Biochemistry, Enzyme, Biology, Chemistry, L-Lactate dehydrogenase

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