Hepatitis E virus: The cause of a waterbourne hepatitis outbreak
Susan J. Skidmore, Patrice O. Yarbough, K.A. Gabor, Gregory R. Reyes
Abstract
Susan J. Skidmore, Patrice O. Yarbough, K.A. Gabor, Gregory R. Reyes
Abstract
Newly developed assays for antibody to hepatitis E virus (HEV) were used to study 114 serum samples collected during an outbreak of enterically transmitted hepatitis that occurred in Kashmir in 1978/9. The sera included samples from patients with viral hepatitis, anicteric hepatitis, contacts of cases, and unaffected persons. A total of 71% of patients with viral hepatitis were found positive for anti-HEV specific IgG, and 75% of these were also positive for IgM. These data confirm the hepatitis E virus as the causative agent in this outbreak.
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Newly developed assays for antibody to hepatitis E virus (HEV) were used to study 114 serum samples collected during an outbreak of enterically transmitted hepatitis that occurred in Kashmir in 1978/9. The sera included samples from patients with viral hepatitis, anicteric hepatitis, contacts of cases, and unaffected persons. A total of 71% of patients with viral hepatitis were found positive for anti-HEV specific IgG, and 75% of these were also positive for IgM. These data confirm the hepatitis E virus as the causative agent in this outbreak.
Key concepts: Virology, Hepatitis E virus, Outbreak, Hepatitis A, Hepatitis, Viral hepatitis, Medicine, Antibody