Sophie B. Heidenhain, Yoshihiro Hayakawa
Abstract
Improved methods of preparing 2′-deoxyribonucleoside and ribonucleoside 3′-phosphoramidites with allylic protecting groups, which serve as useful building blocks, particularly for the synthesis of base-labile derivatives, are developed.
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Improved methods of preparing 2′-deoxyribonucleoside and ribonucleoside 3′-phosphoramidites with allylic protecting groups, which serve as useful building blocks, particularly for the synthesis of base-labile derivatives, are developed.
Key concepts: Ribonucleoside, Deoxyribonucleoside, Allylic rearrangement, Chemistry, Base (topology), Combinatorial chemistry, Biochemistry, Mathematics