2007•Drug Metabolism and DispositionRequires access

Characterization and Comparative Studies of Zebrafish and Human Recombinant Dihydrofolate Reductases—Inhibition by Folic Acid and Polyphenols

Tseng-Ting Kao, Kuan-Chieh Wang, Wen-Ni Chang, Chia-Ying Lin, Bing‐Hung Chen, Hua-Lin Wu, Guey-Yueh Shi, Jen‐Ning Tsai, Tzu-Fun Fu

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Key concepts: Dihydrofolate reductase, Antifolate, Zebrafish, Biology, Biochemistry, Methotrexate, Enzyme, Antimetabolite

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Characterization and Comparative Studies of Zebrafish and Human Recombinant Dihydrofolate Reductases—Inhibition by Folic Acid and Polyphenols — Research Paper | ScholarLens