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2008•Current Topics in Medicinal ChemistryRequires access

Pharmacogenomics and Personalized Use of Drugs

Jingfang Wang, Dong‐Qing Wei, Kuo‐Chen Chou

Open publisher page 37 citations

Abstract

As the development of the Human Genome Project (HGP), the sequencing of whole human genome has been completed, and a series of human genes have been detected, both of which result in the naissance of pharmacogenomics. Pharmacogenomics is the study of how an individuals genetic inheritance affects the bodys response to drugs using the information of human genomics and bioinformatics approaches. It is not only propitious to the rational use of drugs, but also in favor for the personalized drug design. Keywords: Pharmacogenomics, personalized use of drugs, single nucleotide polymorphisms, drug metabolism

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What this paper is about

As the development of the Human Genome Project (HGP), the sequencing of whole human genome has been completed, and a series of human genes have been detected, both of which result in the naissance of pharmacogenomics. Pharmacogenomics is the study of how an individuals genetic inheritance affects the bodys response to drugs using the information of human genomics and bioinformatics approaches. It is not only propitious to the rational use of drugs, but also in favor for the personalized drug design. Keywords: Pharmacogenomics, personalized use of drugs, single nucleotide polymorphisms, drug metabolism

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OpenAlex reports 37 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

As the development of the Human Genome Project (HGP), the sequencing of whole human genome has been completed, and a series of human genes have been detected, both of which result in the naissance of pharmacogenomics. Pharmacogenomics is the study of how an individuals genetic inheritance affects the bodys response to drugs using the information of human genomics and bioinformatics approaches. It is not only propitious to the rational use of drugs, but also in favor for the personalized drug design. Keywords: Pharmacogenomics, personalized use of drugs, single nucleotide polymorphisms, drug metabolism

Key concepts: Pharmacogenomics, Personalized medicine, Human genome, Drug response, Pharmacogenetics, Human genetics, Genomics, Computational biology

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