Sildenafil as a treatment for pulmonary hypertension
Will Carroll
Abstract
Open-access reader
Will Carroll
Abstract
Open-access reader
Severe, chronic pulmonary hypertension in childhood is uncommon, difficult to treat, and carries a poor prognosis. Sildenafil (Viagra, Pfizer) has been used successfully in adults with pulmonary hypertension as monotherapy or in combination with inhaled prostacyclin. Here we report on its use in three children.
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Severe, chronic pulmonary hypertension in childhood is uncommon, difficult to treat, and carries a poor prognosis. Sildenafil (Viagra, Pfizer) has been used successfully in adults with pulmonary hypertension as monotherapy or in combination with inhaled prostacyclin. Here we report on its use in three children.
Key concepts: Medicine, Sildenafil, Pulmonary hypertension, Prostacyclin, Persistent pulmonary hypertension, Intensive care medicine, Pediatrics, Internal medicine