2003Archives of Disease in ChildhoodOpen access

Sildenafil as a treatment for pulmonary hypertension

Will Carroll

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Abstract

Severe, chronic pulmonary hypertension in childhood is uncommon, difficult to treat, and carries a poor prognosis. Sildenafil (Viagra, Pfizer) has been used successfully in adults with pulmonary hypertension as monotherapy or in combination with inhaled prostacyclin. Here we report on its use in three children.

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What this paper is about

Severe, chronic pulmonary hypertension in childhood is uncommon, difficult to treat, and carries a poor prognosis. Sildenafil (Viagra, Pfizer) has been used successfully in adults with pulmonary hypertension as monotherapy or in combination with inhaled prostacyclin. Here we report on its use in three children.

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Available abstract

Severe, chronic pulmonary hypertension in childhood is uncommon, difficult to treat, and carries a poor prognosis. Sildenafil (Viagra, Pfizer) has been used successfully in adults with pulmonary hypertension as monotherapy or in combination with inhaled prostacyclin. Here we report on its use in three children.

Key concepts: Medicine, Sildenafil, Pulmonary hypertension, Prostacyclin, Persistent pulmonary hypertension, Intensive care medicine, Pediatrics, Internal medicine

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