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2012•Nature Structural & Molecular BiologyOpen access

Experimental conditions can obscure the second high-affinity site in LeuT

Matthias Quick, Lei Shi, Britta Zehnpfennig, Harel Weinstein, Jonathan A. Javitch

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Key concepts: Symporter, Aquifex aeolicus, Binding site, Allosteric regulation, Substrate (aquarium), Chemistry, Crystallography, Cooperative binding

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