2009•Inorganic ChemistryRequires access
Mononuclear CuII−Phenolate Bioinspired Complex is Catalytically Promiscuous: Phosphodiester and Peptide Amide Bond Cleavage
Maurício César Bof de Oliveira, Deise J. Mazera, Marciela Scarpellini, Patrícia Severino, Ademir Neves, Hernán Terenzi
Open publisher page 33 citations
Abstract
In this work, the cleavage activity of the metal complex [Cu(C(21)H(21)N(3)O(2))(OH(2))(2)](2+) is demonstrated to occur toward double-stranded DNA, in addition to its previously described amide bond cleavage activity, thus suggesting catalytic promiscuity for this complex.