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2014•The AAPS JournalOpen access

Elucidation of Arctigenin Pharmacokinetics After Intravenous and Oral Administrations in Rats: Integration of In Vitro and In Vivo Findings via Semi-mechanistic Pharmacokinetic Modeling

Qiong Gao, Yufeng Zhang, Siukwan Wo, Zhong Zuo

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Key concepts: Pharmacokinetics, Glucuronidation, Microsome, In vivo, Pharmacology, Chemistry, Enterohepatic circulation, In vitro

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Elucidation of Arctigenin Pharmacokinetics After Intravenous and Oral Administrations in Rats: Integration of In Vitro and In Vivo Findings via Semi-mechanistic Pharmacokinetic Modeling — Research Paper | ScholarLens