Is Axillary Sonographic Staging Less Accurate in Invasive Lobular Breast Cancer Than in Ductal Breast Cancer?
Prashant Sankaye, Sharmila Chhatani, Gareth Porter, J Steel, Sarah Doyle
Abstract
Prashant Sankaye, Sharmila Chhatani, Gareth Porter, J Steel, Sarah Doyle
Abstract
OBJECTIVES: The purpose of this study was to determine whether axillary sonography is less accurate in invasive lobular breast cancer than in ductal breast cancer. METHODS: Patients with invasive breast cancer were retrospectively identified from histologic records from 2010 to 2012. Staging axillary sonograms from 96 patients with primary breast cancer in each of 2 subgroups, invasive lobular carcinoma (ILC) and invasive ductal carcinoma (IDC), were reviewed. Preoperative sonographically guided 14-gauge core biopsy was performed on morphologically abnormal lymph nodes. RESULTS: Thirty-one of 96 patients (32%) in each subgroup were node positive on final postoperative histopathologic analysis. Axillary staging sensitivity was 17 of 31 patients (54%) in the IDC subgroup and 15 of 31(48%) in the ILC subgroup. Further analysis of the data showed no statistically significant differences between these subgroups. CONCLUSIONS: We found that there was no statistically significant difference in the accuracy of axillary sonographic staging between ILC and IDC.
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OBJECTIVES: The purpose of this study was to determine whether axillary sonography is less accurate in invasive lobular breast cancer than in ductal breast cancer. METHODS: Patients with invasive breast cancer were retrospectively identified from histologic records from 2010 to 2012. Staging axillary sonograms from 96 patients with primary breast cancer in each of 2 subgroups, invasive lobular carcinoma (ILC) and invasive ductal carcinoma (IDC), were reviewed. Preoperative sonographically guided 14-gauge core biopsy was performed on morphologically abnormal lymph nodes. RESULTS: Thirty-one of 96 patients (32%) in each subgroup were node positive on final postoperative histopathologic analysis. Axillary staging sensitivity was 17 of 31 patients (54%) in the IDC subgroup and 15 of 31(48%) in the ILC subgroup. Further analysis of the data showed no statistically significant differences between these subgroups. CONCLUSIONS: We found that there was no statistically significant difference in the accuracy of axillary sonographic staging between ILC and IDC.
Key concepts: Medicine, Breast cancer, Invasive lobular carcinoma, Radiology, Invasive ductal carcinoma, Ductal carcinoma, Axilla, Biopsy