Quinidine Therapy and Digitalis Toxicity
Dante E. Manyari, Christopher Patterson, David E. Johnson, Libardo J. Meléndez
Abstract
Dante E. Manyari, Christopher Patterson, David E. Johnson, Libardo J. Meléndez
Abstract
In a 90-year-old man undergoing prolonged digitalis therapy, digitalis toxicity was precipitated by the administration of quinidine. The electrocardiogram revealed supraventricular bidirectional tachycardia, a rare but characteristic arrhythmia associated with digitalis toxicity. Upon withdrawal of digoxin, the clinical and ECG signs disappeared. A diagnosis of digitalis toxicity rather than quinidine intolerance led to appropriate treatment.
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In a 90-year-old man undergoing prolonged digitalis therapy, digitalis toxicity was precipitated by the administration of quinidine. The electrocardiogram revealed supraventricular bidirectional tachycardia, a rare but characteristic arrhythmia associated with digitalis toxicity. Upon withdrawal of digoxin, the clinical and ECG signs disappeared. A diagnosis of digitalis toxicity rather than quinidine intolerance led to appropriate treatment.
Key concepts: Quinidine, Digitalis Toxicity, Medicine, Digitalis, Toxicity, Digoxin, Tachycardia, Ventricular tachycardia