2007•Cancer CellOpen access

Targeted Inactivation of Mdm2 RING Finger E3 Ubiquitin Ligase Activity in the Mouse Reveals Mechanistic Insights into p53 Regulation

Koji Itahana, Hua Mao, Aiwen Jin, Yoko Itahana, Hilary V. Clegg, Mikael S. Lindström, Krishna Bhat, Virginia Godfrey, Gérard I. Evan, Yanping Zhang

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Key concepts: Ubiquitin ligase, Mdm2, Ubiquitin, Mutant, Cell biology, Biology, Ring finger, Ubiquitin-Protein Ligases

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Targeted Inactivation of Mdm2 RING Finger E3 Ubiquitin Ligase Activity in the Mouse Reveals Mechanistic Insights into p53 Regulation — Research Paper | ScholarLens