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2004•Infection Genetics and EvolutionRequires access

Two mutations in dihydrofolate reductase combined with one in the dihydropteroate synthase gene predict sulphadoxine–pyrimethamine parasitological failure in Ugandan children with uncomplicated falciparum malaria

Ambrose Talisuna, Anne Kazibwe, Peter Langi, Theonest K. Mutabingwa, William W. Watkins, Eric Van Marck, Thomas G. Egwang, Umberto D’Alessandro

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Key concepts: DHPS, Dihydropteroate synthase, Dihydrofolate reductase, Pyrimethamine, Biology, Plasmodium falciparum, Sulfadoxine, Point mutation

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Two mutations in dihydrofolate reductase combined with one in the dihydropteroate synthase gene predict sulphadoxine–pyrimethamine parasitological failure in Ugandan children with uncomplicated falciparum malaria — Research Paper | ScholarLens