Evaluation of Rubella Virus Immunoglobulin G (IgG) and IgM Assays with the New Vidia Instrument
Maria Cristina Medici, Monica Martinelli, Valeria Albonetti, Carlo Chezzi, G. Dettori
Abstract
Maria Cristina Medici, Monica Martinelli, Valeria Albonetti, Carlo Chezzi, G. Dettori
Abstract
For rubella virus immunoglobulin G (IgG) and IgM detection, Vidia assays were compared to Vidas, AxSYM, and Liaison assays with 419 serum samples. Only Vidia produced a sensitivity of 100% for IgG and IgM. Vidia specificities were 98.4% for IgG and 99.8% for IgM, versus Vidas specificities of 100 and 99.3%. Vidia IgG and IgM assays performed equally well.
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For rubella virus immunoglobulin G (IgG) and IgM detection, Vidia assays were compared to Vidas, AxSYM, and Liaison assays with 419 serum samples. Only Vidia produced a sensitivity of 100% for IgG and IgM. Vidia specificities were 98.4% for IgG and 99.8% for IgM, versus Vidas specificities of 100 and 99.3%. Vidia IgG and IgM assays performed equally well.
Key concepts: Immunoglobulin M, Rubella, Rubella virus, Immunoglobulin G, Antibody, Togaviridae, Virology, Virus