1965•Experimental Biology and MedicineRequires access

Erythropoietic Stimulating Factor (ESF) Associated with an Oncogenic Virus-Host System in vitro.

F. E. Leaders, Alvar A. Werder, Christopher Schmidt, Mario Castro

Abstract

The possibility that erythropoietic stimulating factor (ESF) might be involved in the relationship between tumor and virus was tested in vitro. Four experimental situations were studied: (A) Adenovirus, type 12 inoculated into hamster cell culture, (B) Adenovirus, type 4 into hamster cell culture, (C) Adenovirus, type 12 into monkey cell culture and (D) Adenovirus, type 4 into monkey cell culture. Each of these cultures was extracted and assayed for ESF. In addition, other cultures containing only virus or cells in medium or medium alone were extracted and assayed.

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Key concepts: Hamster, In vitro, Cell culture, Biology, Virology, Virus, Tissue culture, Adenoviridae