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Double‐step repetitive stimulation in myasthenia gravis

James M. Gilchrist, Donald B. Sanders

Open publisher page 26 citations

Abstract

The double-step technique of repetitive nerve stimulation was compared with repetitive nerve stimulation to a distal and a proximal muscle and with single fiber needle electromyography in 10 patients with myasthenia gravis. We conclude that the double-step technique is slightly more sensitive than repetitive nerve stimulation to a proximal muscle but only 60% as sensitive as single fiber electromyography in demonstrating abnormal neuromuscular transmission in myasthenia gravis.

About this research paper

What this paper is about

The double-step technique of repetitive nerve stimulation was compared with repetitive nerve stimulation to a distal and a proximal muscle and with single fiber needle electromyography in 10 patients with myasthenia gravis. We conclude that the double-step technique is slightly more sensitive than repetitive nerve stimulation to a proximal muscle but only 60% as sensitive as single fiber electromyography in demonstrating abnormal neuromuscular transmission in myasthenia gravis.

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OpenAlex reports 26 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The double-step technique of repetitive nerve stimulation was compared with repetitive nerve stimulation to a distal and a proximal muscle and with single fiber needle electromyography in 10 patients with myasthenia gravis. We conclude that the double-step technique is slightly more sensitive than repetitive nerve stimulation to a proximal muscle but only 60% as sensitive as single fiber electromyography in demonstrating abnormal neuromuscular transmission in myasthenia gravis.

Key concepts: Myasthenia gravis, Repetitive nerve stimulation, Electromyography, Neuromuscular transmission, Stimulation, Medicine, Neuromuscular junction, Nerve stimulation

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