2005•Cancer Chemotherapy and PharmacologyRequires access

Effects and interaction of 7-hydroxy methotrexate and methotrexate in leukaemic cells ex vivo measured by the thymidylate synthase inhibition assay

Rainer Lingg, Georg Hempel, Marianne G. Rots, Christine H. van Zantwijk, Joachim Boos, Gertjan J.L. Kaspers

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Key concepts: Thymidylate synthase, Methotrexate, Antifolate, Metabolite, In vivo, Ex vivo, Chemistry, Pharmacology

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Effects and interaction of 7-hydroxy methotrexate and methotrexate in leukaemic cells ex vivo measured by the thymidylate synthase inhibition assay — Research Paper | ScholarLens