1973•Experimental Biology and MedicineRequires access
Inactivation of Human Interferon by Body Fluids
Thomas C. Cesario, Alexis J. Mandell, Jeremiah G. Tilles
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Abstract
Description of the effects of human feces, bile, saliva, serum, and cerebrospinal fluid on interferon activity. It is shown that crude interferon is inactivated by at least 50% more than with the control medium used, when incubated for 4 hr in vitro in the presence of serum, saliva, or cerebrospinal liquid, and by close to 100% when incubated with stool extract or bile.