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2012•Biophysical JournalOpen access

Cardiomyopathy-Related Mutations (E244D, K247R, D270N, and K273E) in the H2-Helix of Cardiac Troponin T Have Varied Effects on Myofilament Responsiveness to Calcium and Crossbridge Recruitment Dynamics

Steven J. Ford, Srilakshmi Mallampalli, Murali Chandra

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Key concepts: Myofilament, Troponin complex, CrossBridge, Sarcomere, Troponin, Troponin T, Troponin C, Cardiac muscle

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Cardiomyopathy-Related Mutations (E244D, K247R, D270N, and K273E) in the H2-Helix of Cardiac Troponin T Have Varied Effects on Myofilament Responsiveness to Calcium and Crossbridge Recruitment Dynamics — Research Paper | ScholarLens