1981•Mutation research. Fundamental and molecular mechanisms of mutagenesisRequires access

Nitrite converts 2-amino-α-carboline, an indirect mutagen, into 2-hydroxy-α-carboline, a non-mutagen and 2-hydroxy-3-nitroso-α-carboline, a direct mutagen

Matsuhiro Tsuda, Minako Nagao, Takeshi Hirayama, T Sugimura

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Key concepts: Mutagen, Chemistry, Nitroso, Nitrite, Microsome, Nitroso Compounds, Biochemistry, Carcinogen

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Nitrite converts 2-amino-α-carboline, an indirect mutagen, into 2-hydroxy-α-carboline, a non-mutagen and 2-hydroxy-3-nitroso-α-carboline, a direct mutagen — Research Paper | ScholarLens