2005Antimicrobial Agents and ChemotherapyOpen access

In Vitro Activities of Amphotericin B and Voriconazole against Aleurioconidia from Aspergillus terreus

Cornelia Lass‐Flörl, Alexandra Rief, Sandra Leitner, Cornelia Speth, Reinhard Würzner, Manfred Paul Dierich

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Abstract

This study used aleurioconidia as inoculum and compared the MICs of amphotericin B and voriconazole to those obtained for conidia of 31 Aspergillus terreus strains. For conidia and aleurioconidia, the MIC at which 90% of strains were inhibited was 2.5 microg/ml and 5 microg/ml with amphotericin B and 1 microg/ml and 2 microg/ml with voriconazole.

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What this paper is about

This study used aleurioconidia as inoculum and compared the MICs of amphotericin B and voriconazole to those obtained for conidia of 31 Aspergillus terreus strains. For conidia and aleurioconidia, the MIC at which 90% of strains were inhibited was 2.5 microg/ml and 5 microg/ml with amphotericin B and 1 microg/ml and 2 microg/ml with voriconazole.

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Available abstract

This study used aleurioconidia as inoculum and compared the MICs of amphotericin B and voriconazole to those obtained for conidia of 31 Aspergillus terreus strains. For conidia and aleurioconidia, the MIC at which 90% of strains were inhibited was 2.5 microg/ml and 5 microg/ml with amphotericin B and 1 microg/ml and 2 microg/ml with voriconazole.

Key concepts: Aspergillus terreus, Voriconazole, Amphotericin B, Microbiology, Conidium, Aspergillus, In vitro, Fungi imperfecti

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