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2013•Plant Signaling & BehaviorOpen access

Effects of strigolactone-biosynthesis inhibitor TIS108 onArabidopsis

Shinsaku Ito, Mikihisa Umehara, Atsushi Hanada, Shinjiro Yamaguchi, Tadao Asami

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Abstract

TIS108 is a triazole-type strigolactone (SL)-biosynthesis inhibitor that reduces the level of 2'-epi-5-deoxystrigol (epi-5DS) in rice. Here we report the effects of TIS108 on Arabidopsis. Treatment of TIS108 increased the number of branches and repressed root hair elongation as was observed in SL-deficient mutants, and co-application of GR24, a synthetic SL analog, recovered the TIS108-induced phenotype to that of wild-type. In addition, MAX3 and MAX4 genes in the SL-biosynthesis pathway were upregulated in TIS108-treated Arabidopsis, probably due to feedback regulation caused by SL deficiency. These results indicate that TIS108 is an effective tool for regulating SL production in Arabidopsis.

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TIS108 is a triazole-type strigolactone (SL)-biosynthesis inhibitor that reduces the level of 2'-epi-5-deoxystrigol (epi-5DS) in rice. Here we report the effects of TIS108 on Arabidopsis. Treatment of TIS108 increased the number of branches and repressed root hair elongation as was observed in SL-deficient mutants, and co-application of GR24, a synthetic SL analog, recovered the TIS108-induced phenotype to that of wild-type. In addition, MAX3 and MAX4 genes in the SL-biosynthesis pathway were upregulated in TIS108-treated Arabidopsis, probably due to feedback regulation caused by SL deficiency. These results indicate that TIS108 is an effective tool for regulating SL production in Arabidopsis.

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Available abstract

TIS108 is a triazole-type strigolactone (SL)-biosynthesis inhibitor that reduces the level of 2'-epi-5-deoxystrigol (epi-5DS) in rice. Here we report the effects of TIS108 on Arabidopsis. Treatment of TIS108 increased the number of branches and repressed root hair elongation as was observed in SL-deficient mutants, and co-application of GR24, a synthetic SL analog, recovered the TIS108-induced phenotype to that of wild-type. In addition, MAX3 and MAX4 genes in the SL-biosynthesis pathway were upregulated in TIS108-treated Arabidopsis, probably due to feedback regulation caused by SL deficiency. These results indicate that TIS108 is an effective tool for regulating SL production in Arabidopsis.

Key concepts: Arabidopsis, Strigolactone, Biology, Mutant, Biosynthesis, Arabidopsis thaliana, Wild type, Downregulation and upregulation

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