2013•MoleculesOpen access
An Efficient Synthesis of Aldohexose-Derived Piperidine Nitrones: Precursors of Piperidine Iminosugars
Hui Jun Zhao, Wenbo Zhao, Jian‐She Zhu, Yue‐Mei Jia, Chu‐Yi Yu
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Abstract
D-glucopyranose-derived and L-idopyranose-derived piperidine nitrones were synthesized in good overall yields through six-step reaction sequence starting from readily available 2,3,4,6-tetra-O-benzyl-D-glucopyranose. The method is efficient and could be general for the synthesis of aldohexose-derived piperidine nitrones which are precursors of piperidine iminosugars.
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