2012•International Journal of Molecular SciencesOpen access

Structural Elucidation and Bioactivity of Biflavonoids from the Stems of Wikstroemia taiwanensis

Li‐Yin Chen, Ih‐Sheng Chen, Chien‐Fang Peng

Abstract

Three new biflavonoids, wikstaiwanones A-C (1-3), along with four known compounds (4-7) were isolated from the stems of Wikstroemia taiwanensis (Thymelaeaceae). Their structures were elucidated by spectroscopic analysis. Compounds 4 and 5 showed antitubercular activity against Mycobacterium tuberculosis with MIC values of 15 μg/mL, respectively.

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Key concepts: Biflavonoids, Thymelaeaceae, Traditional medicine, Chromone, Chemistry, Medicine, Biology, Stereochemistry