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X-ray and 2D NMR analyses of the binding of nitrogen-containing bisphosphonate drugs to human FPPS

Jean‐Michel Rondeau, Francis Bitsch, E. Bourgier, Martin Geiser, René Hemmig, M. Kroemer, S. Lehmann, Paul Ramage, S. Rieffel, A. Strauß, J.R. Green, Wolfgang Jahnke

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Key concepts: Mevalonate pathway, Farnesyl pyrophosphate, Geranylgeraniol, Prenylation, Farnesol, Isopentenyl pyrophosphate, Chemistry, Biochemistry

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X-ray and 2D NMR analyses of the binding of nitrogen-containing bisphosphonate drugs to human FPPS — Research Paper | ScholarLens