1972•American Journal of AnatomyRequires access

Evidence for spontaneous axon degeneration during peripheral nerve maturation

Paul J. Reier, Arthur Hughes

Abstract

Abstract Ultrastructural examination of sciatic nerves from postnatal mice and rats revealed myelinated and nonmyelinated fibers with structural characteristics similar to those seen in Wallerian degeneration. Such fibers are more commonly found between 7 and 14 days and are believed to represent spontaneous axon degenerations during development.

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Available abstract

Key concepts: Wallerian degeneration, Axon, Degeneration (medical), Sciatic nerve, Axonal degeneration, Ultrastructure, Peripheral, Peripheral nerve