2010•Russian Journal of Bioorganic ChemistryRequires access

Subtyping of influenza virus A hemagglutinin with a hybridization microarray

V. A. Ryabinin, Е. В. Костина, G. A. Maksakova, A. N. Sinyakov

Abstract

An oligonucleotide microarray for influenza A hemagglutinine subtyping was presented. The number of probes for determination of each subtype hemagglutinine (H1-H13, H15, H16, pandemic flu H1N1)varied from 13 to 28. When testing of the microarray using 40 type A influenza virus isolates the hemagglutinin subtypes were unambiguously determined for 36 specimens.

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Key concepts: Subtyping, Hemagglutinin (influenza), Virology, Virus, Influenza A virus, Biology, Microarray, H5N1 genetic structure