Recombinant Plasmodium falciparum dihydrofolate reductase-based in vitro screen for antifolate antimalarials
Reynolds Brobey, Gen‐ichiro Sano, Fumio Itoh, Kazuyoshi Aso, Masatsugu Kimura, T. Mitamura, Toshihiro Horii
Abstract
Reynolds Brobey, Gen‐ichiro Sano, Fumio Itoh, Kazuyoshi Aso, Masatsugu Kimura, T. Mitamura, Toshihiro Horii
Abstract
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Key concepts: Dihydrofolate reductase, Antifolate, Pyrimethamine, Plasmodium falciparum, Plasmodium berghei, Biology, Escherichia coli, Enzyme