1998Bioorganic & Medicinal Chemistry LettersOpen access

Diarylsulfonamides as selective, non-peptidic thrombin inhibitors

Ingo R. Weber, Richard Neidlein, Wolfgang von der Saal, Frank Grams, Herbert Leinert, K. Strein, Richard A. Engh, Ralf Kucznierz

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Key concepts: Thrombin, Chemistry, Discovery and development of direct thrombin inhibitors, Trypsin, Plasmin, Stereochemistry, Biochemistry, Enzyme

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