Regular and relayed heteronuclear correlations by a single two‐dimensional experiment involving an RF gradient

Abstract In order to achieve a better suppression of signals arising from protons non‐bonded to the considered heteronucleus, two (π/4) proton pulses are used in the HMQC sequence: one, at the very beginning, replaces the classical (π/2) pulse and the other is at the end of the sequence. In addition, a spin‐lock purging period improves the elimination process. This novel sequence is shown to provide the conventional heteronuclear correlations and, in addition, relayed homonuclear (proton–proton) correlations. A simple methodology capable of sorting out both types of correlations is proposed. However, this procedure entails a sensitivity loss by a factor of two.