1962•Radiation ResearchRequires access

The Relative Biological Effectiveness of 22-Mevp X-Rays, Cobalt-60 Gamma Rays, and 200-Kvcp X-Rays: IV. Determined by Effects on the Iron-59 Uptake in Rats

Warren K. Sinclair, Linda Blackwell, Ronald M. Humphrey

Abstract

A series of six simultaneous experiments was conducted with Co/sup 60/ gamma rays and 22-Mevp and 200-kvcp x rays. Fe/sup 59/ was injected at the optimum time for each dose level, and the l5-day uptake thereafter was determined. The effectiveness of the radiations was compared by choosing a comparable effectiveness level (ED/sub 50/) on the linear response curve. The average of six experiments yielded RBE values of 0.85 for Co/sup 60/ gamma rays versus 200-kvcp x rays, 0.84 for 22-Mewp x rays versus 200-kvcp x rays, and 0.99 for 22-Mevp x rays versus Co/sup 60/ gamma rays, based on the absorbed dose to soft tissue. (auth)

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Key concepts: Cobalt-60, Gamma ray, Radiochemistry, Roentgen rays, Isotopes of cobalt, Cobalt, Relative biological effectiveness, X-ray