2003•BloodRequires access

Lack of alteration in GATA-1 expression in CD34+ hematopoietic progenitors from patients with idiopathic myelofibrosis

Marie‐Claire Martyré, Virginie Steunou, Marie-Caroline Lebousse-Kerdiles, Juana Wietzerbin

Abstract

Idiopathic myelofibrosis (IM), also known as myelofibrosis with myeloid metaplasia, is a myeloproliferative disorder of clonal origin characterized by extramedullary hematopoiesis with a leukoerythroblastic blood picture, tear-drop erythrocytes, and progressive splenomegaly associated with bone

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Available abstract

Key concepts: Myelofibrosis, Extramedullary hematopoiesis, Haematopoiesis, CD34, Myeloid, Metaplasia, Medicine, Pathology