2013•VaccineOpen access

Construction, characterization and preclinical evaluation of MTBVAC, the first live-attenuated M. tuberculosis-based vaccine to enter clinical trials

Ainhoa Arbués, Juan I. Aguilo, Jesús Gonzalo‐Asensio, Dessislava Marinova, Santiago Uranga, Eugenia Puentes, Conchita Fernandez, Alberto Parra, Père-Joan Cardona, Cristina Vilaplana, Vicente Ausina, Ann Williams, Simon O Clark, Wladimir Malaga, Christophe Guilhot, Brigitte Gicquel, Carlos Martı́n

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Key concepts: Mycobacterium tuberculosis, Tuberculosis, Tuberculosis vaccines, Virulence, Attenuated vaccine, Virology, BCG vaccine, Clinical trial