1982Antimicrobial Agents and ChemotherapyOpen access

Serum assays of netilmicin by enzyme multiplied immunoassay technique and bioassay: a comparative study

Lauren M. Jansson, C Henning

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Abstract

Serum concentration determinations of netilmicin obtained with bioassay and the enzyme multiplied immunoassay technique were compared. There was no statistically significant difference between the precision of the two techniques (P greater than 0.05). When clinical serum was used, a systematic error was demonstrated between the enzyme multiplied immunoassay technique and bioassay.

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Serum concentration determinations of netilmicin obtained with bioassay and the enzyme multiplied immunoassay technique were compared. There was no statistically significant difference between the precision of the two techniques (P greater than 0.05). When clinical serum was used, a systematic error was demonstrated between the enzyme multiplied immunoassay technique and bioassay.

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Available abstract

Serum concentration determinations of netilmicin obtained with bioassay and the enzyme multiplied immunoassay technique were compared. There was no statistically significant difference between the precision of the two techniques (P greater than 0.05). When clinical serum was used, a systematic error was demonstrated between the enzyme multiplied immunoassay technique and bioassay.

Key concepts: Netilmicin, Bioassay, Immunoassay, Chromatography, Enzyme, Chemistry, Radioimmunoassay, Medicine

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