Calculations of double spike isotope dilution results revisited
Juris Meija, Lu Yang, Joseph A. Caruso, Zoltán Mester
Abstract
Juris Meija, Lu Yang, Joseph A. Caruso, Zoltán Mester
Abstract
The use of isotope pattern deconvolution analysis is proposed to simplify the double spiking species-specific isotope dilution result calculations when inter-conversion might occur. A detailed example is given for the determination of Cr(III)/Cr(VI) in yeast by isotope dilution-HPLC-ICP-MS. The results are in exact agreeent with the conventional isotope dilution calculations.
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The use of isotope pattern deconvolution analysis is proposed to simplify the double spiking species-specific isotope dilution result calculations when inter-conversion might occur. A detailed example is given for the determination of Cr(III)/Cr(VI) in yeast by isotope dilution-HPLC-ICP-MS. The results are in exact agreeent with the conventional isotope dilution calculations.
Key concepts: Isotope dilution, Isotope, Dilution, Chemistry, Deconvolution, Analytical Chemistry (journal), Chromatography, Radiochemistry