1992•Bioorganic & Medicinal Chemistry LettersRequires access

MDL 74147, a novel selective and soluble inhibitor of human renin. Synthesis, structure-activity relationship, species and protease selectivities.

Daniel Schirlin, Céline Tarnus, Sylvie Baltzer, Jean-Marc Rémy

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Key concepts: Chemistry, Renin inhibitor, Enzyme inhibitor, Chemical synthesis, Structure–activity relationship, Renin–angiotensin system, Protease, Stereochemistry

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MDL 74147, a novel selective and soluble inhibitor of human renin. Synthesis, structure-activity relationship, species and protease selectivities. — Research Paper | ScholarLens