1999•Phytochemical AnalysisRequires access

Seasonal variations in the content of taxanes in the bark of Taxus baccata L.

Daniela Veselá, David Šaman, Irena Valterová, Tomáš Van??k

Abstract

Analytical determination by HPLC of five taxanes—paclitaxel, cephalomannine, 10-deacetylpaclitaxel, 10-deacetylcephalomannine and taxcultine—in extracts from the bark of Taxus baccata indicates that taxane concentrations vary seasonally. The highest concentration was found in October and the lowest in January for all taxanes examined. Copyright © 1999 John Wiley & Sons, Ltd.

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Key concepts: Taxus, Taxane, Chemistry, Bark (sound), Paclitaxel, Botany, Forestry, Cancer