ScholarLens Back to search
1978•Bulletin of the Chemical Society of JapanRequires access

Modification of Aminocyclitol Antibiotics. 6. Preparation of 5-Deoxykanamycin B

Tetsuo Suami, Shigeru Nishiyama, Yasuhide Ishikawa, Eijiro Umemura

Open publisher page 15 citations

Abstract

Abstract Aminocyclitol antibiotic kanamycin B has been modified as regards the aminocyclitol moiety by removing a hydroxyl group on C-5. 5-Deoxykanamycin B thus obtained was tested against several microorganisms. The structure of 5-deoxykanamycin B was established by mass and 13C NMR spectrometry. 5,6,3′,4′-Tetradeoxyneamine was prepared as a reference compound for 13C NMR spectrometry.

About this research paper

What this paper is about

Abstract Aminocyclitol antibiotic kanamycin B has been modified as regards the aminocyclitol moiety by removing a hydroxyl group on C-5. 5-Deoxykanamycin B thus obtained was tested against several microorganisms. The structure of 5-deoxykanamycin B was established by mass and 13C NMR spectrometry. 5,6,3′,4′-Tetradeoxyneamine was prepared as a reference compound for 13C NMR spectrometry.

Why it matters

OpenAlex reports 15 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Abstract Aminocyclitol antibiotic kanamycin B has been modified as regards the aminocyclitol moiety by removing a hydroxyl group on C-5. 5-Deoxykanamycin B thus obtained was tested against several microorganisms. The structure of 5-deoxykanamycin B was established by mass and 13C NMR spectrometry. 5,6,3′,4′-Tetradeoxyneamine was prepared as a reference compound for 13C NMR spectrometry.

Key concepts: Aminocyclitol, Chemistry, Kanamycin, Moiety, Mass spectrometry, Antibiotics, Stereochemistry, Aminoglycoside

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Modification of Aminocyclitol Antibiotics. 6. Preparation of 5-Deoxykanamycin B — Research Paper | ScholarLens