Duloxetine for the treatment of fibromyalgia
Cheryl L. Wright, Scott Mist, Rebecca L. Ross, Kim Dupree Jones
Abstract
Cheryl L. Wright, Scott Mist, Rebecca L. Ross, Kim Dupree Jones
Abstract
This article presents a brief review of the physiologic abnormalities seen in fibromyalgia, current theories of widespread pain, and treatment options, including emerging therapeutics, with a focus on the use of duloxetine to manage fibromyalgia symptoms. Major clinical trials that examine the efficacy and effectiveness of duloxetine to date are reviewed, and safety issues are discussed.
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This article presents a brief review of the physiologic abnormalities seen in fibromyalgia, current theories of widespread pain, and treatment options, including emerging therapeutics, with a focus on the use of duloxetine to manage fibromyalgia symptoms. Major clinical trials that examine the efficacy and effectiveness of duloxetine to date are reviewed, and safety issues are discussed.
Key concepts: Duloxetine, Fibromyalgia, Medicine, Clinical trial, Intensive care medicine, Alternative medicine, Physical therapy, Internal medicine