2010Expert Review of Clinical ImmunologyOpen access

Duloxetine for the treatment of fibromyalgia

Cheryl L. Wright, Scott Mist, Rebecca L. Ross, Kim Dupree Jones

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Abstract

This article presents a brief review of the physiologic abnormalities seen in fibromyalgia, current theories of widespread pain, and treatment options, including emerging therapeutics, with a focus on the use of duloxetine to manage fibromyalgia symptoms. Major clinical trials that examine the efficacy and effectiveness of duloxetine to date are reviewed, and safety issues are discussed.

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What this paper is about

This article presents a brief review of the physiologic abnormalities seen in fibromyalgia, current theories of widespread pain, and treatment options, including emerging therapeutics, with a focus on the use of duloxetine to manage fibromyalgia symptoms. Major clinical trials that examine the efficacy and effectiveness of duloxetine to date are reviewed, and safety issues are discussed.

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OpenAlex reports 43 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

This article presents a brief review of the physiologic abnormalities seen in fibromyalgia, current theories of widespread pain, and treatment options, including emerging therapeutics, with a focus on the use of duloxetine to manage fibromyalgia symptoms. Major clinical trials that examine the efficacy and effectiveness of duloxetine to date are reviewed, and safety issues are discussed.

Key concepts: Duloxetine, Fibromyalgia, Medicine, Clinical trial, Intensive care medicine, Alternative medicine, Physical therapy, Internal medicine

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