1973•EndocrinologyRequires access

Serum Testosterone and Dihydrotestosterone Levels Following Orchiectomy in the Adult Rat

Juan Coyotupa, Albert F. Parlow, N. Kovačić

Abstract

Serum concentration of testosterone (T) in 24 normal adult male rats, expressed as mean ± SD, was 5.5 ± 2.7 ng/ml. In the same animals mean dihydrotestosterone (DHT) was 0.35 ± 0.18 ng/ml. Within 5 min after orchiectomy, serum T concentration had decreased to 55.5% of the initial "control" value. Within 2 hr after orchiectomy serum T was undetectable (less than 0.06 ng/ml) in 4 of 6 animals. Twenty—four hr after orchiectomy, serum T was undetectable in 7 of 8 animals. Serum DHT concentrations decreased similarly after orchiectomy. (Endocrinology92: 1579, 1973)

About this research paper

What this paper is about

Why it matters

OpenAlex reports 55 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Orchiectomy, Dihydrotestosterone, Endocrinology, Internal medicine, Testosterone (patch), Medicine, Adult male, Serum concentration