The Toxicity Assay of Artemia salina as a Biological Model for the Preliminary Toxic Evaluation of Chemical Pollutants
Yin Lu, Xiaolu Xu, Chao Meng, Jia Zhou, Jun Jie Sheng, Chen Kang Wu, Shu Wen Xu
Abstract
Yin Lu, Xiaolu Xu, Chao Meng, Jia Zhou, Jun Jie Sheng, Chen Kang Wu, Shu Wen Xu
Abstract
In order to achieve a good correlation between toxicology andArtemia salinalethality test, several chemical pollutants were examined inA. salinatest, with the purpose to use the latter as convenient preliminary protocol for toxic activity. During the test, it was observed the effect of a particular lethal dose or only a knockdown in the arthropod of HgCl2, KCN, K2Cr2O7, C6H6and C6H6Cl6. The 24h LC50of these five chemical pollutants to theartemianauplius was 0.12±0.09, 0.06±0.12, 0.72±0.21, 1.57±0.58 and 0.44±0.10 mg/L, respectively. The results of theA. salinalethality test for the chemical substances are essentially in agreement with those described in literature for toxic activity.
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In order to achieve a good correlation between toxicology andArtemia salinalethality test, several chemical pollutants were examined inA. salinatest, with the purpose to use the latter as convenient preliminary protocol for toxic activity. During the test, it was observed the effect of a particular lethal dose or only a knockdown in the arthropod of HgCl2, KCN, K2Cr2O7, C6H6and C6H6Cl6. The 24h LC50of these five chemical pollutants to theartemianauplius was 0.12±0.09, 0.06±0.12, 0.72±0.21, 1.57±0.58 and 0.44±0.10 mg/L, respectively. The results of theA. salinalethality test for the chemical substances are essentially in agreement with those described in literature for toxic activity.
Key concepts: Artemia salina, Pollutant, Toxicity, Bioassay, Toxicology, Chemistry, Environmental chemistry, Biology