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2010•Natural Product ResearchRequires access

A novel antimicrobial agent from the leaves ofPeltophorum vogelianum(Benth.)

Mehtab Parveen, Raza Murad Ghalib, Zakia Khanam, Sayed Hasan Mehdi, Mohammad Ali

Open publisher page 35 citations

Abstract

The methanolic extract of the leaves of Peltophorum vogelianum (Caesalpiniaceae) afforded a new phytoconstituent, 2-methoxy-4,5-dihydroxy-1(7,8-dihydroxyethylene)-8-beta-D-glucuropyranoside named as peltophorumyl-beta-D-glucuropyranoside (5), along with four known phytoconstituents, 1-pentatriacontanol (1), friedelin (2), beta-sitosterol (3) and beta-sitosterol-beta-D-glucopyranoside (4), which have not been isolated previously from this plant. Their structures were established on the basis of chemical and physical evidence (IR, 1H-NMR, 13C-NMR, DEPT, HSQC, HMBC and MS). Moreover, compound 5 showed significant antimicrobial activity.

About this research paper

What this paper is about

The methanolic extract of the leaves of Peltophorum vogelianum (Caesalpiniaceae) afforded a new phytoconstituent, 2-methoxy-4,5-dihydroxy-1(7,8-dihydroxyethylene)-8-beta-D-glucuropyranoside named as peltophorumyl-beta-D-glucuropyranoside (5), along with four known phytoconstituents, 1-pentatriacontanol (1), friedelin (2), beta-sitosterol (3) and beta-sitosterol-beta-D-glucopyranoside (4), which have not been isolated previously from this plant. Their structures were established on the basis of chemical and physical evidence (IR, 1H-NMR, 13C-NMR, DEPT, HSQC, HMBC and MS). Moreover, compound 5 showed significant antimicrobial activity.

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OpenAlex reports 35 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The methanolic extract of the leaves of Peltophorum vogelianum (Caesalpiniaceae) afforded a new phytoconstituent, 2-methoxy-4,5-dihydroxy-1(7,8-dihydroxyethylene)-8-beta-D-glucuropyranoside named as peltophorumyl-beta-D-glucuropyranoside (5), along with four known phytoconstituents, 1-pentatriacontanol (1), friedelin (2), beta-sitosterol (3) and beta-sitosterol-beta-D-glucopyranoside (4), which have not been isolated previously from this plant. Their structures were established on the basis of chemical and physical evidence (IR, 1H-NMR, 13C-NMR, DEPT, HSQC, HMBC and MS). Moreover, compound 5 showed significant antimicrobial activity.

Key concepts: Friedelin, DEPT, Antimicrobial, Chemistry, Heteronuclear single quantum coherence spectroscopy, Stereochemistry, Carbon-13 NMR, Traditional medicine

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