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Controlled Trial Comparing Effect of Two and Six Weeks' Treatment in Recurrent Urinary Tract Infection

Priscilla Kincaid‐Smith, Kenneth F. Fairley

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Abstract

Patients with recurrent urinary tract infection were allocated at random to two weeks' or six weeks' treatment with an appropriate antibacterial drug. There was no difference in the results achieved by the two different periods of treatment as judged by the presence of infection in the urine one week and six weeks after treatment was stopped.The urine was clear of infection in a higher percentage of patients following a course of nitrofurantoin than following a course of ampicillin, but the difference was not significant.

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What this paper is about

Patients with recurrent urinary tract infection were allocated at random to two weeks' or six weeks' treatment with an appropriate antibacterial drug. There was no difference in the results achieved by the two different periods of treatment as judged by the presence of infection in the urine one week and six weeks after treatment was stopped.The urine was clear of infection in a higher percentage of patients following a course of nitrofurantoin than following a course of ampicillin, but the difference was not significant.

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Available abstract

Patients with recurrent urinary tract infection were allocated at random to two weeks' or six weeks' treatment with an appropriate antibacterial drug. There was no difference in the results achieved by the two different periods of treatment as judged by the presence of infection in the urine one week and six weeks after treatment was stopped.The urine was clear of infection in a higher percentage of patients following a course of nitrofurantoin than following a course of ampicillin, but the difference was not significant.

Key concepts: Nitrofurantoin, Urinary system, Medicine, Urine, Ampicillin, Significant difference, Antibiotics, Clinical trial

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