2009•SynthesisRequires access

Expedient Reductive Amination of Aldehyde Bisulfite Adducts

Neelakandha S. Mani, Chennagiri R. Pandit

Abstract

A novel, one-pot protocol for the direct reductive amination of aldehyde bisulfite adducts is reported. Bisulfite adducts of aliphatic and aromatic aldehydes, on treatment with an organic base under non-aqueous conditions liberate the aldehyde in situ, which then undergoes efficient reductive amination with amines in the presence of sodium triacetoxyborohydride.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 11 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Chemistry, Sodium bisulfite, Aldehyde, Reductive amination, Bisulfite, Adduct, Amination, Organic chemistry