Non-genetic expression of adolescent idiopathic scoliosis: a case report and review of the literature
Joris P.S. Hermus, Lodewijk W. van Rhijn, André van Ooij
Abstract
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Joris P.S. Hermus, Lodewijk W. van Rhijn, André van Ooij
Abstract
Open-access reader
Treating children with idiopathic scoliosis can amaze someone at the many different ways in which the deformity can present. Most authors state that genetics stipulates the course of adolescent idiopathic scoliosis. This is mainly based on the high concordance in monozygotic twins. However, there is indication that environmental factors have influences on adolescent idiopathic scoliosis. This is the first report in which a monozygotic twin pair is described concordant for idiopathic scoliosis but with different apical levels, magnitudes and age at detection of scoliosis which stresses the importance of environmental factors.
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Treating children with idiopathic scoliosis can amaze someone at the many different ways in which the deformity can present. Most authors state that genetics stipulates the course of adolescent idiopathic scoliosis. This is mainly based on the high concordance in monozygotic twins. However, there is indication that environmental factors have influences on adolescent idiopathic scoliosis. This is the first report in which a monozygotic twin pair is described concordant for idiopathic scoliosis but with different apical levels, magnitudes and age at detection of scoliosis which stresses the importance of environmental factors.
Key concepts: Scoliosis, Idiopathic scoliosis, Medicine, Concordance, Deformity, Congenital scoliosis, Spinal deformity, Neurosurgery