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Heterogeneity in Epidermal Basal Keratinocytes: Morphological and Functional Correlations

Robert M. Lavker, Tung‐Tien Sun

Open publisher page 398 citations

Abstract

Two structurally distinct populations of basal keratinocytes, nonserrated and serrated, were observed in cynomolgus monkey and human palm epidermis. Anatomical location, fine structural features, and kinetic properties suggest that nonserrated cells represent a stem cell population and that serrated cells help anchor the epidermis to the dermis.

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What this paper is about

Two structurally distinct populations of basal keratinocytes, nonserrated and serrated, were observed in cynomolgus monkey and human palm epidermis. Anatomical location, fine structural features, and kinetic properties suggest that nonserrated cells represent a stem cell population and that serrated cells help anchor the epidermis to the dermis.

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Available abstract

Two structurally distinct populations of basal keratinocytes, nonserrated and serrated, were observed in cynomolgus monkey and human palm epidermis. Anatomical location, fine structural features, and kinetic properties suggest that nonserrated cells represent a stem cell population and that serrated cells help anchor the epidermis to the dermis.

Key concepts: Epidermis (zoology), Basal (medicine), Dermis, Biology, Keratinocyte, Population, Palm, Anatomy

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